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Eclipta prostrata 

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Synonyms : 

  • Eclipta prostrata (L.) L.

  • Eclipta alba HASSK.

  • Eclipta erecta L.

Common name :False Daisy, babri, jalmagra, mochkand
  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No
Phytochemical Name
Phytochemical ID
Synonym
2D structure
3D structure
Part
1
Wedelolactone
CID_5281813
N.A
Leaves
2
Demethylwedelolactone
CID_5489605
1,3,8,9-Tetrahydroxy-6H-benzofuro[3,2-c]chromen-6-one Norwedelolactone
3
Isodemethylwedelolactone
CID_5318547
Isodemethylwedelolacton
Whole plant
4
Strychnolactone
N.A
5
Demethylwedelolactone glucoside
N.A
Aerial parts
6
Eclalbasaponin I
CID_10079039
N.A
7
Eclalbasaponin II
N.A
8
Eclalbasaponins III
CID_10418425
N.A
9
Eclalbasaponins IV
N.A
10
Eclalbasaponins V
N.A
12
Eclalbasaponins VII
N.A
11
Eclalbasaponins VI
N.A
13
Eclalbasaponins VIII
CID_102446071
N.A
14
Eclalbasaponins IX
CID_102446073
N.A
15
Eclalbasaponin X
CID_102446074
N.A
16
Eclalbasaponins XI
CID_50561538
17
Eclalbasaponin XII
CID_52176904
8
Eclalbasaponins XII
CID_52176904
19
Eclalbasaponins XIII
CID_51801068
20
Eclalbasaponin A
N.A
21
Eclalbasaponins B
N.A
22
Eclalbasaponin C
N.A
23
Eclalbasaponin D
N.A
29
3β-Hydroxy-17-epi-28-norolean-12-en-16-one 3-O-β-D-glucopyranoside
N.A
28
16α-Hydroxy-olean-12-en-3-on-28,21β-olide
N.A
27
3β,25-Dihydroxy-23E-lemmaphyll-8,23-diene
N.A
Whole plant
26
Eclalbatin
N.A
25
Echinocystic acid-3-O-(6-O-acetyl)-β-D-glucopyranoside
N.A
Aerial parts
24
Echinocystic acid
CID_73309
N.A
30
3β-O-(6-O-Crotonyl-β-D-glucopyranosyl)-16α-hydroxyolean-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester
N.A
36
3-O-β-D-Glucopyranosyl-(1-2)-β-D-glucopyranosyl oleanlic-18- ene acid-28-O-β-D-glucopyranoside
N.A
35
3,28-di-O-β-D-Glucopyranosyl-3β,16β-dihydroxy oleanane-12-ene-28-oleanlic acid
N.A
34
3-O-(β-D-Glucopyranosyl) oleanolic acid-28-O-(6-O-acetyl-β-D-glucopyranosyl) ester
N.A
33
3-O-(β-D-Glucopyranosyl) oleanolic acid-28-O-(6-O-acetyl-β-D-glucopyranosyl) ester
N.A
32
3-O-(6-O-Acetyl-β-D-glucopyranosyl) oleanolic acid-28-O-(β-D-glucopyranosyl) ester
N.A
31
3-O-(2-O-Acetyl-β-D-glucopyranosyl) oleanolic acid-28-O-(β-D-glucopyranosyl) ester
N.A
Aerial parts
42
20-epi-25β-Hydroxyverazin
N.A
41
20-epi-4β-Hydroxyverazine
N.A
40
(20R)-25β-Hydroxyverazine
N.A
39
(20R)-20-Pyridyl-cholesta-5-ene-3β,23-diol (Ecliptalbine)
CID_10692897
38
20-epi-3-Dehydroxy-3-oxo-5,6-dihydro-4,5-dehydroverazine
N.A
37
(20S)(25S)-22,26-Imino-cholesta-5,22(N)-dien-3β-ol (Verazine)
CID_161052
Leaves
48
Oleanolic acid
CID_10494
Oleanic acid Caryophyllin Astrantiagenin C
47
Ursolic acid
CID_64945
46
α-Amyrin
CID_73170
Viminalol
45
Lanost-5,24-dien-3β-ol-18, 21-olide -3β- yl tetradecanoate
N.A
Whole plant
44
25β-Hydroxyverazine
CID_10549683
N.A
43
20-epi-25β-Hydroxyverazine
N.A
49
3-Oxo-16α-hydroxy-olean-12-en-28-oic acid
N.A
50
Machaeroceric acid
CID_21604186
N.A
51
Silphioside C
CID_21607684
Whole plant
52
β-Sitosterol
CID_222284
Sitosterol Cupreol Azuprostat
53
Stigmasterol
CID_5280794
Leaves
54
Stigmasterol-3-O-glucoside
N.A
55
3-O-(60-O-Palmitoyl-β-D-glucopyranosyl) stigmasterol
N.A
56
Daucosterol
CID_5742590
Sitogluside
Leaves
57
Luteolin
CID_5280445
Aerial part
58
Kaempferol
CID_5280863
Robigenin
Whole plant
59
Quercetin
CID_5280343
Meletin Sophoretin Quercetine
Aerial parts
60
Vanillic acid
CID_8468
Acide vanillique p-Vanillic acid
Aerial parts
61
Caffeic acid
CID_689043
3,4-Dihydroxycinnamic acid
Whole plant

The IC50 value of compound 5 against PGE2 release was found to be 49.6 μm, whereas it was inactive towards TNF-α (IC50 > 100 μm).

Source : Timalsina et al.,2021

Disclaimer: The main motive behind the construction of this database is to compile information from the scientific literature on Indian medicinal plants to aid ongoing research efforts in the field of computational drug discovery.The curated data should be used only for research purposes and not for any self-diagnosis or any medical treatment.

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