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WITHANIA SOMNIFERA 

Common name : Ashwagandha 
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Frequently asked questions

S.No
Phytochemical Name
Phytochemical ID
Synonym
part
2D structure
3D structure
Medicinal uses
1
(-)-ANAFERINE
CID_443143
Root
2
(22R)-14,20,27-Trihydroxy-22,26-epoxyergosta-2,5,24-triene-1,26-dione
Plant
3
(22R)-14,20-Dihydroxy-22,26-epoxyergosta-3,5,24-triene-1,26-dione
Plant
4
2,3-Didehydrosomnifericin
CID_70684083
plant
5
2,3-Dihydro-3beta-methoxy withaferin A
CID_10767792
3beta-Methoxy-2,3-dihydrowithaferin A, Quresimine A
Root
6
2,3-Dihydrowithaferin A
CID_15411208
2,3-Dihydro-Withaferin A
leaf
7
2,3-Dihydrowithanolide E
CID_131751517
Leaf
8
2,4-METHYLENE-CHOLESTEROL
CID_92113
Chalinasterol, 24-Methylenecholesterol, Ostreasterol
tissue culture
9
3-ALPHA-TIGLOYLOXYTROPANE
CID_12444363
Tropigline, Tigloidine, tigloidin
Root
10
4.beta.-Hydroxywithanolide
CID_476483
Leaf
Antimelanomic Antitumor
11
4beta-Hydroxywithanolide E
CID_73621
4beta-Hydroxywithanolide E 4-beta-Hydroxywithanolide E 4beta-hydroxywithanolide
12
4-DEOXYPHYSALOLACTONE
CID_13743195
6-Chloro-5,14,17,20-tetrahydroxy-1-oxowitha-2,24-dienolide
Shoot

The calculated IC50 values for 24hr are 350μg/ml, for 48 hr is 250 μg/ml and for 72 hr is 200μg/ml. So from this data it can be said that reduction of the cell viability is a dose as well as time dependent phenomena due to Withania somnifera crude extract treatment.

Source : Adaikkapp et al.,2012

Source for phytochemicals : Duke's and pubchem 

Disclaimer: The main motive behind the construction of this database is to compile information from the scientific literature on Indian medicinal plants to aid ongoing research efforts in the field of computational drug discovery.The curated data should be used only for research purposes and not for any self-diagnosis or any medical treatment.

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