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AMMPDB VER.1.1
WITHANIA SOMNIFERA
Common name : Ashwagandha

ashwagandha-plant


seeds

ashwagandha-plant
1/8

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S.No | Phytochemical Name | Phytochemical ID | Synonym | part | 2D structure | 3D structure | Medicinal uses |
|---|---|---|---|---|---|---|---|
1 | (-)-ANAFERINE | CID_443143 | Root | ||||
2 | (22R)-14,20,27-Trihydroxy-22,26-epoxyergosta-2,5,24-triene-1,26-dione | Plant | |||||
3 | (22R)-14,20-Dihydroxy-22,26-epoxyergosta-3,5,24-triene-1,26-dione | Plant | |||||
4 | 2,3-Didehydrosomnifericin | CID_70684083 | plant | ||||
5 | 2,3-Dihydro-3beta-methoxy withaferin A | CID_10767792 | 3beta-Methoxy-2,3-dihydrowithaferin A,
Quresimine A | Root | |||
6 | 2,3-Dihydrowithaferin A | CID_15411208 | 2,3-Dihydro-Withaferin A | leaf | |||
7 | 2,3-Dihydrowithanolide E | CID_131751517 | Leaf | ||||
8 | 2,4-METHYLENE-CHOLESTEROL | CID_92113 | Chalinasterol,
24-Methylenecholesterol,
Ostreasterol | tissue culture | |||
9 | 3-ALPHA-TIGLOYLOXYTROPANE | CID_12444363 | Tropigline,
Tigloidine,
tigloidin | Root | |||
10 | 4.beta.-Hydroxywithanolide | CID_476483 | Leaf | Antimelanomic
Antitumor | |||
11 | 4beta-Hydroxywithanolide E | CID_73621 | 4beta-Hydroxywithanolide E
4-beta-Hydroxywithanolide E
4beta-hydroxywithanolide | ||||
12 | 4-DEOXYPHYSALOLACTONE | CID_13743195 | 6-Chloro-5,14,17,20-tetrahydroxy-1-oxowitha-2,24-dienolide | Shoot | |||
13 | 17alpha-Hydroxywithanolide | CID_23266161 | |||||
14 | 17-ALPHA-HYDROXYWITHANOLIDE | CID_44423097 | |||||
15 | 24-ETHYLCHOLEST-5-EN-3-BETA-OL | CID_22012 | Stigmast-5-en-3-ol | ||||
16 | 24-ETHYLCHOLESTA-5-(Z)-24(28)-DIEN-3-BETA-OL | CID_5281326 | Isofucosterol,
Fucosterol,
delta5-Avenasterol,
Delta 5-avenasterol,
28-Isofucosterol | ||||
17 | 24-Methylcholesta-5,23E-dien-3beta-ol | CID_5283652 | |||||
18 | 24-METHYLCHOLESTA-5,24-DIEN-3BETA-OL | CID_193567 | |||||
19 | 27-Deoxywithaferin A | CID_23266155 | |||||
20 | 27-Hydroxywithanolide B | CID_15858981 | Isofucosterol
Fucosterol
delta5-Avenasterol
Delta 5-avenasterol
28-Isofucosterol | ||||
21 | ANAFERINE | CID_440934 | Anapheline | Root | |||
22 | ANAHYGRINE | CID_12306778 | Root | ||||
23 | BETA-SITOSTEROL | CID_222284 | Sitosterol,
Cupreol,
Azuprostat | Tissue culture, root, leaf | Antibacterial
Anticancer
Antitumor
Antiviral | ||
24 | CAMPESTEROL | CID_173183 | Campesterin | Tissue culture | Antioxidant
Hypocholesterolemic | ||
25 | CHLOROGENIC-ACID | CID_1794427 | 3-O-Caffeoylquinic acid,
3-(3,4-Dihydroxycinnamoyl)quinic acid,
Heriguard | Leaf | Antibacterial
Anticancer
Antidiabetic
Antimutagenic
Antioxidant
Antiseptic | ||
26 | CHOLINE | CID_305 | Choline ion,
Bilineurine | Root | Antidiabetic
Antidementia | ||
27 | Cryptochlorogenic acid | CID_9798666 | 4-Caffeoylquinic acid,
4-O-Caffeoylquinic acid | ||||
28 | CUSCOHYGRINE | CID_1201543 | meso-Cuscohygrine | ||||
29 | DAUCOSTEROL | CID_5742590 | Sitogluside,
Eleutheroside A, Alexandrin | Fruit | Antileukemic
Antispasmodic
Antitumor | ||
30 | DULCITOL | CID_11850 | galactitol,dulcite,
D-Galactitol | Antitumor | |||
31 | Hentriacontane_3D | CID_12410 | |||||
32 | Hentriacontane | CID_12410 | n-Hentriacontane, Untriacontane,
n-Hentriacontanone | ||||
33 | HYDROXYPROLINE | CID_5810 | L-Hydroxyproline,
trans-4-Hydroxy-L-proline | Fruit | vulnerary | ||
34 | HYGRINE | CID_440933 | Root | ||||
35 | ISOCHLOROGENIC-ACID-C | CID_6474309 | 4,5-Dicaffeoylquinic acid | Leaf | |||
36 | ISOPELLETIERINE | CID_92987 | Pelletierine, dl-Pelletierine,
1-(Piperidin-2-yl)propan-2-one | Root | Amblyopic
Emetic
Laxative
Mydriatic | ||
37 | LINOLEIC-ACID_3D | CID_5280450 | Plant | ||||
38 | LINOLEIC-ACID | CID_5280450 | Linolic acid, Telfairic acid | Plant | Antiandrogenic
Anti-inflammatory
cancer preventive | ||
39 | NICOTINE | CID_89594 | L-Nicotine, (S)-Nicotine | Root | Analgesic
Anti fumitory
Epinephrininergic | ||
40 | Pseudotropine_3D | CID_449293 | Root | ||||
41 | Pubesenolide | CID_72999858 | |||||
42 | Quercetin 3-rutinoside-7-glucoside | CID_10190763 | Quercetin 3-rhamnoglucoside 7-beta-glucoside | Leaf | Analgesic
Antiaging
Antiallergic
Antibacterial
Antidiabetic | ||
43 | QUERCETIN | CID_5280343 | Meletin,
Sophoretin,
Xanthaurine | ||||
44 | QUINIC-ACID | CID_6508 | Leaf | Choleretic | |||
45 | Quresimine A | Plant | |||||
46 | Quresimine B | Plant | |||||
47 | RUTIN | CID_5280805 | rutoside,
Phytomelin,
Quercetin 3-rutinoside | Leaf | Antiallergic
Antibacterial
Anticancer
Antidiabetic | ||
48 | SCOPOLETIN | CID_5280460 | Gelseminic acid,
7-Hydroxy-6-methoxy-2H-chromen-2-one,
6-Methylesculetin. | plant | Antibacterial
Antiedema
Antiseptic
Antioxidant | ||
49 | SITOINDOSIDE-IX | CID_189586 | Root | Immunostimulant
Antistress | |||
50 | SITOINDOSIDE-X | CID_189702 | 4-hydroxy-1,26-dioxo-5,6:22,26-diepoxyergosta-2,24-dien-27-yl 6-o-hexadecanoylhexopyranoside | Root | immunostimulant
Antistress | ||
51 | SOMNIFERANOLIDE | CID_102066415 | Stem bark | ||||
52 | SOMNIFERAWITHANOLIDE | CID_102066416 | Stem bark | ||||
53 | Somnifericin | CID_101687980 | Plant | ||||
54 | SOMNIFERINE | CID_14106343 | Root | Hypnotic
Sedative | |||
55 | SOMNIWITHANOLIDE | CID_102066417 | Stem bark | ||||
56 | STEARIC-ACID | CID_5281 | Octadecanoic acid,Stearophanic acid,
n-Octadecanoic acid | Hypocholesterolemic | |||
57 | Stigmasta-5,24(28)-dien-3-ol | CID_66739275 | Stigmasta-5,24(28)-dien-3-ol | ||||
58 | STIGMASTEROL | CID_5280794 | Stigmasterin , beta-Stigmasterol | tissue culture, plant | Antihepatotooxic
Anti-inflammatory
Anti-oxidant
Antiviral | ||
59 | TROPINE | CID_8424 | Pseudotropine,
8-Methyl-8-azabicyclo[3.2.1]octan-3-ol | Root | |||
60 | WITHACNISTIN | CID_54606507 | Leaf | Antitumor | |||
61 | WITHAFERIN-A | CID_265237 | Withaferine A | Root
shoot
leaf
plant | Antibacterial
Anticarcinomic
Anti-inflammatory
Antileukemic
Antiseptic
Antitumor
Antiviral | ||
62 | Withanicandrin | CID_12444955 | Leaf | ||||
63 | WITHANOLIDE F | Leaf | |||||
64 | WITHANOLIDE J | CID_21679022 | Leaf | ||||
65 | WITHANOLIDE K | Leaf | |||||
66 | WITHANOLIDE L | CID_179575 | Leaf | ||||
67 | WITHANOLIDE M | CID_25090669 | Leaf | ||||
68 | WITHANOLIDE P | CID_21679034 | Leaf | ||||
69 | WITHANOLIDE Q | CID_101281365 | Leaf | ||||
70 | WITHANOLIDE R | CID_101281364 | Leaf | ||||
71 | WITHANOLIDE-D | CID_161671 | 5,6-Epoxy-4,20,22-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid delta-lactone | Leaf | Anti-inflammatory
Antiseptic
Antitumor | ||
72 | WITHANOLIDE-E | CID_301751 | Shoot | Antitumor | |||
73 | WITHANOLIDE-G | CID_21679023 | Leaf | ||||
74 | WITHANOLIDE-N | CID_23266147 | Leaf | ||||
75 | WITHANOLIDE-O | CID_23266146 | Leaf | ||||
76 | WITHANOLIDE-S | CID_11049407 | Leaf | ||||
77 | WITHANONE | CID_21679027 | Leaf
shoot | ||||
78 | WITHAOXYLACTONE | CID_101687981 | Plant | ||||
79 | Withasomniferanolide | CID_102066414 | Stem bark | ||||
80 | WITHASOMNIFEROL-A | CID_101710595 | Root | ||||
81 | WITHASOMNIFEROL-B | CID_101710596 | Root | ||||
82 | WITHASOMNIFEROL-C | CID_101710597 | Root | ||||
83 | Withasomnilide | CID_102066413 | Withasomnilide | Stem bark | |||
84 | WITHASOMNINE | CID_442877 | 3-Phenyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole.
4H-Pyrrolo[1,2-b]pyrazole, 5,6-dihydro-3-phenyl- | Plant |
The calculated IC50 values for 24hr are 350μg/ml, for 48 hr is 250 μg/ml and for 72 hr is 200μg/ml. So from this data it can be said that reduction of the cell viability is a dose as well as time dependent phenomena due to Withania somnifera crude extract treatment.
Source : Adaikkapp et al.,2012
Source for phytochemicals : Duke's and pubchem
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